About the Authors

Rahul S. Desikan

rahul@nmr.mgh.harvard.edu

Affiliations Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Radiology, University of California San Diego, La Jolla, California, United States of America

Mert R. Sabuncu

Affiliations Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Computer Science and Artificial Intelligence Laboratory (CSAIL) and Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Nicholas J. Schmansky

Affiliation Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Martin Reuter

Affiliation Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Howard J. Cabral

Affiliation Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America

Christopher P. Hess

Affiliation Department of Radiology, University of California San Francisco, San Francisco, California, United States of America

Michael W. Weiner

Affiliations Department of Radiology, University of California San Francisco, San Francisco, California, United States of America, Department of Veteran Affairs, San Francisco, California, United States of America

Alessandro Biffi

Affiliations Center for Human Genetic Research, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America

Christopher D. Anderson

Affiliations Center for Human Genetic Research, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America

Jonathan Rosand

Affiliations Center for Human Genetic Research, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America

David H. Salat

Affiliation Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Thomas L. Kemper

Affiliation Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts, United States of America

Anders M. Dale

Affiliations Department of Radiology, University of California San Diego, La Jolla, California, United States of America, Department of Neuroscience, University of California San Diego, La Jolla, California, United States of America

Reisa A. Sperling

Affiliations Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Bruce Fischl

Affiliations Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Computer Science and Artificial Intelligence Laboratory (CSAIL) and Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

the Alzheimer's Disease Neuroimaging Initiative

For more information on the Alzheimer's Disease Neuroimaging Initiative please see the Acknowledgments.

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RSD CPH MWW JR TLK AMD RAS BF. Performed the experiments: RSD MRS NJS HJC AB. Analyzed the data: RSD MRS NJS HJC AB CDA DHS. Contributed reagents/materials/analysis tools: MR BF. Wrote the paper: RSD MR CPH MWW AB CDA JR DHS TLK AMD RAS BF.