About the Authors
- Thomas E. Edwards
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* E-mail: tedwards@embios.com
Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America
- Isabelle Phan
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America
- Jan Abendroth
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America
- Shellie H. Dieterich
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America
- Amir Masoudi
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America
- Wenjin Guo
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America
- Stephen N. Hewitt
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, School of Medicine, University of Washington, Seattle, Washington, United States of America
- Angela Kelley
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, School of Medicine, University of Washington, Seattle, Washington, United States of America
- David Leibly
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, School of Medicine, University of Washington, Seattle, Washington, United States of America
- Mitch J. Brittnacher
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Affiliation Departments of Microbiology, Medicine, Genome Sciences, and Immunology, University of Washington, Seattle, Washington, United States of America
- Bart L. Staker
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America
- Samuel I. Miller
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Affiliation Departments of Microbiology, Medicine, Genome Sciences, and Immunology, University of Washington, Seattle, Washington, United States of America
- Wesley C. Van Voorhis
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, School of Medicine, University of Washington, Seattle, Washington, United States of America
- Peter J. Myler
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America
- Lance J. Stewart
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Affiliations Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America
Competing Interests
Several authors of the mansucript (TEE, JA, SHD, BLS, LJS) work for Emerald BioStructures Inc., a commercial company, and are therefore required to declare their affilitation to this company. Emerald is a subcontractor through the Seattle Biomedical Research Institute (SBRI), and PJM is PI on the Seattle Structural Genomics Center for Infectious Disease (SSGCID), which is funded by the National Institute for Allergy and Infectious Disease (NIAID). This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. All materials and data have been made publically available through the appropriate public repositories (e.g. PDB, BEI, targetDB, etc). In addition, these materials may be obtained directly from the authors.
Author Contributions
Conceived and designed the experiments: TEE IP JA BLS SIM WCVV PJM LJS. Performed the experiments: TEE IP JA SHD AM WG SNH AK DL MJB. Analyzed the data: TEE IP JA. Wrote the paper: TEE IP JA BLS.