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Research Article

Comparative Genomics of Gardnerella vaginalis Strains Reveals Substantial Differences in Metabolic and Virulence Potential

  • Carl J. Yeoman,

    Affiliation: Institute for Genomic Biology, University of Illinois, Urbana, Illinois, United States of America

    X
  • Suleyman Yildirim,

    Affiliation: Institute for Genomic Biology, University of Illinois, Urbana, Illinois, United States of America

    X
  • Susan M. Thomas,

    Affiliation: Institute for Genomic Biology, University of Illinois, Urbana, Illinois, United States of America

    X
  • A. Scott Durkin,

    Affiliation: J. Craig Venter Institute, Rockville, Maryland, United States of America

    X
  • Manolito Torralba,

    Affiliation: J. Craig Venter Institute, Rockville, Maryland, United States of America

    X
  • Granger Sutton,

    Affiliation: J. Craig Venter Institute, Rockville, Maryland, United States of America

    X
  • Christian J. Buhay,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Yan Ding,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Shannon P. Dugan-Rocha,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Donna M. Muzny,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Xiang Qin,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Richard A. Gibbs,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Steven R. Leigh,

    Affiliation: Department of Anthropology, University of Illinois, Urbana, Illinois, United States of America

    X
  • Rebecca Stumpf,

    Affiliation: Department of Anthropology, University of Illinois, Urbana, Illinois, United States of America

    X
  • Bryan A. White,

    Affiliations: Institute for Genomic Biology, University of Illinois, Urbana, Illinois, United States of America, Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States of America

    X
  • Sarah K. Highlander,

    Affiliations: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Karen E. Nelson,

    Affiliation: J. Craig Venter Institute, Rockville, Maryland, United States of America

    X
  • Brenda A. Wilson mail

    bawilson@life.illinois.edu

    Affiliations: Institute for Genomic Biology, University of Illinois, Urbana, Illinois, United States of America, Department of Microbiology, University of Illinois, Urbana, Illinois, United States of America

    X
  • Published: August 26, 2010
  • DOI: 10.1371/journal.pone.0012411

About the Authors

Carl J. Yeoman, Suleyman Yildirim, Susan M. Thomas, Bryan A. White, Brenda A. Wilson
Institute for Genomic Biology, University of Illinois, Urbana, Illinois, United States of America
A. Scott Durkin, Manolito Torralba, Granger Sutton, Karen E. Nelson
J. Craig Venter Institute, Rockville, Maryland, United States of America
Christian J. Buhay, Yan Ding, Shannon P. Dugan-Rocha, Donna M. Muzny, Xiang Qin, Richard A. Gibbs, Sarah K. Highlander
Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America
Steven R. Leigh, Rebecca Stumpf
Department of Anthropology, University of Illinois, Urbana, Illinois, United States of America
Bryan A. White
Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States of America
Sarah K. Highlander
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America
Brenda A. Wilson
Department of Microbiology, University of Illinois, Urbana, Illinois, United States of America

Corresponding Author

Email: bawilson@life.illinois.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CJY RAG BAW SKH KEN BAW. Performed the experiments: CJY SY SMT ASD MT GS CB YD SDR DM XQ RAG BAW. Analyzed the data: CJY ASD MT GS CB YD SDR DM XQ BAW. Contributed reagents/materials/analysis tools: CJY SY SMT SRL RS BAW SKH KEN. Wrote the paper: CJY SY SMT ASD SRL RS BAW SKH KEN BAW.