Structural Basis for Certain Naturally Occurring Bioflavonoids to Function as Reducing Co-Substrates of Cyclooxygenase I and II

Pan Wang; Hyoung-Woo Bai; Bao Ting Zhu

doi:10.1371/journal.pone.0012316

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Peer-reviewed

Research Article

Structural Basis for Certain Naturally Occurring Bioflavonoids to Function as Reducing Co-Substrates of Cyclooxygenase I and II

Pan Wang ,

Contributed equally to this work with: Pan Wang, Hyoung-Woo Bai

Affiliation Department of Pharmacology, Toxicology and Therapeutics, School of Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯
Hyoung-Woo Bai ,

Contributed equally to this work with: Pan Wang, Hyoung-Woo Bai

Affiliation Department of Pharmacology, Toxicology and Therapeutics, School of Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯
Bao Ting Zhu

* E-mail: BTZhu@kumc.edu

Affiliation Department of Pharmacology, Toxicology and Therapeutics, School of Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯

Structural Basis for Certain Naturally Occurring Bioflavonoids to Function as Reducing Co-Substrates of Cyclooxygenase I and II

Pan Wang,
Hyoung-Woo Bai,
Bao Ting Zhu

Published: August 23, 2010
https://doi.org/10.1371/journal.pone.0012316

About the Authors

Pan Wang

Contributed equally to this work with: Pan Wang, Hyoung-Woo Bai

Affiliation Department of Pharmacology, Toxicology and Therapeutics, School of Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America

Hyoung-Woo Bai

Contributed equally to this work with: Pan Wang, Hyoung-Woo Bai

Affiliation Department of Pharmacology, Toxicology and Therapeutics, School of Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America

Bao Ting Zhu

* E-mail: BTZhu@kumc.edu

Affiliation Department of Pharmacology, Toxicology and Therapeutics, School of Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PW HWB BTZ. Performed the experiments: PW HWB. Analyzed the data: PW HWB BTZ. Contributed reagents/materials/analysis tools: BTZ. Wrote the paper: PW HWB BTZ.

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Hydrogen bonding
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Molecular structure
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