About the Authors

Yasushi Noguchi

Contributed equally to this work with: Yasushi Noguchi, Natsumi Nishikata, Nahoko Shikata

Affiliations Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Research Institute for Health Fundamentals, Ajinomoto Co. Inc., Kawasaki, Kanagawa, Japan

Natsumi Nishikata

Contributed equally to this work with: Yasushi Noguchi, Natsumi Nishikata, Nahoko Shikata

Affiliation Research Institute for Health Fundamentals, Ajinomoto Co. Inc., Kawasaki, Kanagawa, Japan

Nahoko Shikata

Contributed equally to this work with: Yasushi Noguchi, Natsumi Nishikata, Nahoko Shikata

Affiliation Research Institute for Health Fundamentals, Ajinomoto Co. Inc., Kawasaki, Kanagawa, Japan

Yoshiko Kimura

Affiliation Research Institute for Health Fundamentals, Ajinomoto Co. Inc., Kawasaki, Kanagawa, Japan

Jose O. Aleman

Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Jamey D. Young

Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Naoto Koyama

Affiliation Research Institute for Health Fundamentals, Ajinomoto Co. Inc., Kawasaki, Kanagawa, Japan

Joanne K. Kelleher

Affiliations Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Shriners Burn Hospital, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Michio Takahashi

Affiliation Research Institute for Health Fundamentals, Ajinomoto Co. Inc., Kawasaki, Kanagawa, Japan

Gregory Stephanopoulos

gregstep@mit.edu

Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YN NN NS YK JOA JDY NK JK MT GNS. Performed the experiments: YN NN NS YK JOA. Analyzed the data: YN NN NS JDY NK JK. Contributed reagents/materials/analysis tools: JDY JK MT GNS. Wrote the paper: YN JDY JK MT GNS.