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Research Article

Nuclear S100A7 Is Associated with Poor Prognosis in Head and Neck Cancer

  • Satyendra Chandra Tripathi,

    Affiliation: Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India

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  • Ajay Matta,

    Affiliations: Department of Chemistry, York University, Toronto, Ontario, Canada, Centre for Research in Mass Spectrometry, York University, Toronto, Ontario, Canada

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  • Jatinder Kaur,

    Affiliation: Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India

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  • Jorg Grigull,

    Affiliation: Department of Mathematics and Statistics, York University, Toronto, Ontario, Canada

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  • Shyam Singh Chauhan,

    Affiliation: Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India

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  • Alok Thakar,

    Affiliation: Department of Otorhinolaryngology, All India Institute of Medical Sciences, New Delhi, India

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  • Nootan Kumar Shukla,

    Affiliation: Department of Surgery, Dr. B. R. A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India

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  • Ritu Duggal,

    Affiliation: Department of Dental Surgery, All India Institute of Medical Sciences, New Delhi, India

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  • Siddhartha DattaGupta,

    Affiliation: Department of Pathology, All India Institute of Medical Sciences, New Delhi, India

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  • Ranju Ralhan equal contributor mail,

    equal contributor Contributed equally to this work with: Ranju Ralhan, K. W. Michael Siu

    ralhanr@yorku.ca (RR); kwmsiu@yorku.ca (KWMS)

    Affiliations: Department of Chemistry, York University, Toronto, Ontario, Canada, Centre for Research in Mass Spectrometry, York University, Toronto, Ontario, Canada, Joseph and Mildred Sonshine Family Centre for Head and Neck Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada, Department of Otolaryngology – Head and Neck Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada, Department of Otolaryngology – Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada

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  • K. W. Michael Siu equal contributor mail

    equal contributor Contributed equally to this work with: Ranju Ralhan, K. W. Michael Siu

    ralhanr@yorku.ca (RR); kwmsiu@yorku.ca (KWMS)

    Affiliations: Department of Chemistry, York University, Toronto, Ontario, Canada, Centre for Research in Mass Spectrometry, York University, Toronto, Ontario, Canada

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  • Published: August 03, 2010
  • DOI: 10.1371/journal.pone.0011939

About the Authors

Satyendra Chandra Tripathi, Jatinder Kaur, Shyam Singh Chauhan
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India
Ajay Matta, Ranju Ralhan, K. W. Michael Siu
Department of Chemistry, York University, Toronto, Ontario, Canada
Ajay Matta, Ranju Ralhan, K. W. Michael Siu
Centre for Research in Mass Spectrometry, York University, Toronto, Ontario, Canada
Jorg Grigull
Department of Mathematics and Statistics, York University, Toronto, Ontario, Canada
Alok Thakar
Department of Otorhinolaryngology, All India Institute of Medical Sciences, New Delhi, India
Nootan Kumar Shukla
Department of Surgery, Dr. B. R. A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
Ritu Duggal
Department of Dental Surgery, All India Institute of Medical Sciences, New Delhi, India
Siddhartha DattaGupta
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
Ranju Ralhan
Joseph and Mildred Sonshine Family Centre for Head and Neck Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada
Ranju Ralhan
Department of Otolaryngology – Head and Neck Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada
Ranju Ralhan
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
Ranju Ralhan
Department of Otolaryngology – Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AM RR MS. Performed the experiments: SCT AM. Analyzed the data: SCT AM JK JG SD. Contributed reagents/materials/analysis tools: SSC AT NKS RD SD RR MS. Wrote the paper: SCT AM RR MS.