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Research Article

Oscillations by Minimal Bacterial Suicide Circuits Reveal Hidden Facets of Host-Circuit Physiology

  • Philippe Marguet,

    Affiliation: Department of Biochemistry, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Yu Tanouchi,

    Affiliation: Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States of America

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  • Eric Spitz,

    Affiliation: Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States of America

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  • Cameron Smith,

    Affiliation: Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States of America

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  • Lingchong You mail

    you@duke.edu

    Affiliations: Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States of America, Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Published: July 30, 2010
  • DOI: 10.1371/journal.pone.0011909

About the Authors

Philippe Marguet
Department of Biochemistry, Duke University Medical Center, Durham, North Carolina, United States of America
Yu Tanouchi, Eric Spitz, Cameron Smith, Lingchong You
Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States of America
Lingchong You
Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina, United States of America

Corresponding Author

Email: you@duke.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PM LY. Performed the experiments: PM ES CS. Analyzed the data: PM YT ES CS LY. Contributed reagents/materials/analysis tools: PM YT. Wrote the paper: PM YT LY.