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Research Article

Whole-Genome Sequencing Reveals Distinct Mutational Patterns in Closely Related Laboratory and Naturally Propagated Francisella tularensis Strains

  • Andreas Sjödin,

    Affiliation: Division of CBRN Security and Defence, FOI - Swedish Defence Research Agency, Umeå, Sweden

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  • Kerstin Svensson,

    Affiliation: Division of CBRN Security and Defence, FOI - Swedish Defence Research Agency, Umeå, Sweden

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  • Marie Lindgren,

    Affiliations: Department of Clinical Microbiology and Clinical Bacteriology, Umeå University, Umeå, Sweden, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden

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  • Mats Forsman,

    Affiliation: Division of CBRN Security and Defence, FOI - Swedish Defence Research Agency, Umeå, Sweden

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  • Pär Larsson mail

    par.larsson@foi.se

    Affiliation: Division of CBRN Security and Defence, FOI - Swedish Defence Research Agency, Umeå, Sweden

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  • Published: July 19, 2010
  • DOI: 10.1371/journal.pone.0011556

About the Authors

Andreas Sjödin, Kerstin Svensson, Mats Forsman, Pär Larsson
Division of CBRN Security and Defence, FOI - Swedish Defence Research Agency, Umeå, Sweden
Marie Lindgren
Department of Clinical Microbiology and Clinical Bacteriology, Umeå University, Umeå, Sweden
Marie Lindgren
Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden

Corresponding Author

Email: par.larsson@foi.se

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AS ML PL. Performed the experiments: AS ML. Analyzed the data: AS KS ML PL. Wrote the paper: AS KS MF PL.