About the Authors

Matt T. Bianchi

mtbianchi@partners.org

Affiliation Neurology Department, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Sydney S. Cash

Affiliation Neurology Department, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Joseph Mietus

Affiliation Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

Chung-Kang Peng

Affiliation Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

Robert Thomas

Affiliation Sleep Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

Competing Interests

Dr. Thomas has consulted for Total Sleep Holdings; has a patent for CO2 adjunctive therapy for complex sleep apnea, ECG-based method to assess sleep stability and phenotype sleep apnea; and has financial interests in SomRx. Dr. Thomas, Dr. Peng and Mr. Mietus are part co-inventors of the sleep spectrogram method (licensed by the BIDMC to Embla), and share patent rights and royalties. Mr. Mietus has financial interests in DynaDx Corp. Dr. Peng has financial interests in DynaDx Corp. This does not alter our adherence to all the PLoS ONE policies on sharing data and materials. Dr Bianchi has indicated no financial conflicts of interest.

Author Contributions

Conceived and designed the experiments: MTB SSC RJT. Analyzed the data: MTB SSC JM. Contributed reagents/materials/analysis tools: MTB SSC JM CKP RJT. Wrote the paper: MTB SSC JM CKP RJT.