About the Authors

Marina Gertsenstein

Contributed equally to this work with: Marina Gertsenstein, Lauryl M. J. Nutter

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, The Toronto Centre for Phenogenomics, Toronto, Ontario, Canada

Lauryl M. J. Nutter

Contributed equally to this work with: Marina Gertsenstein, Lauryl M. J. Nutter

Affiliation The Hospital for Sick Children, Toronto, Ontario, Canada

Tammy Reid

Affiliation Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

Monica Pereira

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, The Toronto Centre for Phenogenomics, Toronto, Ontario, Canada

William L. Stanford

Affiliation Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

Janet Rossant

Affiliations The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada

Andras Nagy

nagy@mshri.on.ca

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MG LMJN TR MP JR. Performed the experiments: MG LMJN TR MP. Analyzed the data: MG LMJN TR MP JR. Contributed reagents/materials/analysis tools: MG LMJN TR WLS AN. Wrote the paper: MG LMJN JR. Reviewed the manuscript: TR MP WLS. Provided expert advice: AN WLS JR. Conceived the targeting allele: AN.