About the Authors

Tatiana Falcone

Affiliation Cleveland Clinic-Lerner College of Medicine, Cleveland, Ohio, United States of America

Vincent Fazio

Affiliation Cleveland Clinic-Lerner College of Medicine, Cleveland, Ohio, United States of America

Catherine Lee

Affiliation Cleveland Clinic-Lerner College of Medicine, Cleveland, Ohio, United States of America

Barry Simon

Affiliation Cleveland Clinic-Lerner College of Medicine, Cleveland, Ohio, United States of America

Kathleen Franco

Affiliation Cleveland Clinic-Lerner College of Medicine, Cleveland, Ohio, United States of America

Nicola Marchi

Affiliation Cleveland Clinic-Lerner College of Medicine, Cleveland, Ohio, United States of America

Damir Janigro

janigrd@ccf.org

Affiliation Cleveland Clinic-Lerner College of Medicine, Cleveland, Ohio, United States of America

Competing Interests

Dr. Damir Janigro, who developed the S-100β test and will get payments relating to this technology, is the principal investigator on this research study, and has a financial interest in Roche Diagnostics, whose product is being tested in this research. Further information on Roche Diagnostics can be found at the following web link: http://www.roche.com/about_roche/business_fields/about-diagnostics.htm. Damir Janigro, Ph.D. is Chairman of the Board of Scientific Advisors at Flocel, Inc. and his responsibilities include overseeing the testing service at The Cleveland Clinic Foundation laboratories, consulting for Flocel customers and new product development. In exchange for the investment of his time and contribution to the development of the technology, he has received 90-100 shares of stock with additional stock granted based on company performance. Further information on Flocel, Inc. can be found at the following web link: http://www.flocel.com/. These competing interests do not affect Dr. Janigro's adherence to all the PLoS ONE policies on sharing data and materials, as detailed online at http://www.plosone.org/static/policies.action#sharing.

Author Contributions

Conceived and designed the experiments: TF BS KF DJ. Performed the experiments: VF. Analyzed the data: VF CL BS NM DJ. Contributed reagents/materials/analysis tools: DJ. Wrote the paper: TF VF CL BS KF NM DJ.