About the Authors

Michael L. Nickerson

nickersonml@mail.nih.gov (MLN); jweiss@med.wayne.edu (JSW)

Affiliations Cancer and Inflammation Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America, Graduate Partnership Program, National Institutes of Health, Bethesda, Maryland, United States of America, Molecular Medicine Program, Institute for Biomedical Sciences, George Washington University, Washington, D. C., United States of America

Brittany N. Kostiha

Affiliations Cancer and Inflammation Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America, Biomedical Science Graduate Program, Hood College, Frederick, Maryland, United States of America

Wolfgang Brandt

Affiliation Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale), Germany

William Fredericks

Affiliation Division of Urology, Department of Surgery, University of Pennsylvania and Veterans Affairs Medical Center, Philadelphia, Pennsylvania, United States of America

Ke-Ping Xu

Affiliation Kresge Eye Institute and Department of Ophthalmology, Wayne State University School of Medicine, Detroit, Michigan, United States of America

Fu-Shin Yu

Affiliation Kresge Eye Institute and Department of Ophthalmology, Wayne State University School of Medicine, Detroit, Michigan, United States of America

Bert Gold

Affiliation Cancer and Inflammation Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America

James Chodosh

Affiliation Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Cambridge, Massachusetts, United States of America

Marc Goldberg

Affiliation The Eye Institute, Tulsa, Oklahoma, United States of America

Da Wen Lu

Affiliation Tri-Service General Hospital, Taipei, Taiwan

Masakazu Yamada

Affiliation National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan

Timo M. Tervo

Affiliation Helsinki University Eye Hospital, Helsinki, Finland

Richard Grutzmacher

Affiliation Grutzmacher, Lewis, and Sierra, Sacramento, California, United States of America

Chris Croasdale

Affiliation Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

Maria Hoeltzenbein

Affiliation Max-Planck Institut für Molekulare Genetik, Berlin, Germany

John Sutphin

Affiliation Department of Ophthalmology, University of Kansas Medical Center, Prairie Village, Kansas, United States of America

S. Bruce Malkowicz

Affiliation Division of Urology, Department of Surgery, University of Pennsylvania and Veterans Affairs Medical Center, Philadelphia, Pennsylvania, United States of America

Ludger Wessjohann

Affiliation Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale), Germany

Howard S. Kruth

Affiliation Section of Experimental Atherosclerosis, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Michael Dean

Affiliation Cancer and Inflammation Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America

Jayne S. Weiss

nickersonml@mail.nih.gov (MLN); jweiss@med.wayne.edu (JSW)

Affiliation Kresge Eye Institute and Departments of Ophthalmology and Pathology, Wayne State University School of Medicine, Detroit, Michigan, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MLN WB LW HK JW. Performed the experiments: MLN BNK WB KPX BG LW HK MD. Analyzed the data: MLN BNK WB LW HK JW. Contributed reagents/materials/analysis tools: MLN WF KPX FSY BG JC MAG DWL MY TMT RG CC MH JS SBM LW HK MD JW. Wrote the paper: MLN WB LW HK MD JW.