About the Authors
- Juliet A. Moncaster
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Contributed equally to this work with: Juliet A. Moncaster, Roberto Pineda, Robert D. Moir
Affiliation Molecular Aging & Development Laboratory, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Roberto Pineda
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Contributed equally to this work with: Juliet A. Moncaster, Roberto Pineda, Robert D. Moir
Affiliation Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States of America
- Robert D. Moir
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Contributed equally to this work with: Juliet A. Moncaster, Roberto Pineda, Robert D. Moir
Affiliation Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America
- Suqian Lu
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Affiliation Molecular Aging & Development Laboratory, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Mark A. Burton
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Affiliation Molecular Aging & Development Laboratory, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Joy G. Ghosh
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Affiliation Molecular Aging & Development Laboratory, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Maria Ericsson
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Affiliation Electron Microscopy Facility, Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America
- Stephanie J. Soscia
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Affiliation Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America
- Anca Mocofanescu
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Affiliation Molecular Aging & Development Laboratory, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Rebecca D. Folkerth
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Affiliation Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Richard M. Robb
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Affiliation Department of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States of America
- Jer R. Kuszak
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Affiliation Departments of Ophthalmology and Pathology, Rush University Medical Center, Chicago, Illinois, United States of America
- John I. Clark
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Affiliation Departments of Biological Structure and Ophthalmology, University of Washington, Seattle, Washington, United States of America
- Rudolph E. Tanzi
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Affiliation Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America
- David G. Hunter
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Affiliation Department of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States of America
- Lee E. Goldstein
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* E-mail: LGOLD@BU.EDU
Affiliation Molecular Aging & Development Laboratory, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
Competing Interests
Authors Moncaster, Pineda, Lu, Burton, Ghosh, Ericsson, Soscia, Mocofanescu, Folkerth, Robb, Kuszak, Clark, and Hunter report no conflict of interest. The following authors reported consultant activity during the course of this study: Drs. Tanzi and Goldstein, Neuroptix Corp, Acton, MA; Drs. Moir, Tanzi, and Goldstein, Covance, Dedham, MA. No financial support was provided by any commercial entity for this study.
Author Contributions
Conceived and designed the experiments: JAM RP RDM RMR JIC RET DGH LEG. Performed the experiments: JAM RDM SL MAB JGG ME SJS AM. Analyzed the data: JAM RP RDM MAB ME JK JIC RET DGH LEG. Contributed reagents/materials/analysis tools: JAM RP RDM SL MAB ME RF RMR JK RET DGH LEG. Wrote the paper: JAM RP RDM DGH LEG. Revised the manuscript: JGG AM RF RMR JK JIC RET.