About the Authors
- Ville Härmä
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Affiliation Medical Biotechnology Knowledge Centre, VTT Technical Research Centre of Finland, Turku, Finland
- Johannes Virtanen
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Affiliation Biotechnology Centre, University of Turku, Turku, Finland
- Rami Mäkelä
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Affiliation Medical Biotechnology Knowledge Centre, VTT Technical Research Centre of Finland, Turku, Finland
- Antti Happonen
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Affiliation Knowledge Intensive Services, VTT Technical Research Centre of Finland, Tampere, Finland
- John-Patrick Mpindi
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Affiliation Biotechnology Centre, University of Turku, Turku, Finland
- Matias Knuuttila
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Affiliation Biotechnology Centre, University of Turku, Turku, Finland
- Pekka Kohonen
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Affiliation Biotechnology Centre, University of Turku, Turku, Finland
- Jyrki Lötjönen
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Affiliation Knowledge Intensive Services, VTT Technical Research Centre of Finland, Tampere, Finland
- Olli Kallioniemi
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Affiliation Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
- Matthias Nees
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* E-mail: matthias.nees@vtt.fi
Affiliation Medical Biotechnology Knowledge Centre, VTT Technical Research Centre of Finland, Turku, Finland
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: VVH MN. Performed the experiments: VVH JV RM MK. Analyzed the data: VVH JV AH JPM PK. Contributed reagents/materials/analysis tools: VVH JV RM AH JL OK. Wrote the paper: MN. Scientific supervision and concept: MN. Conceptual and scientific development of the project: VVH. Cell culture: VVH, JV, MK. Microscopy: VVH, JV. Protein biochemistry: VVH, JV, RM, MK. Gene expression analysis: VVH. Bioinformatics: VVH, JPM, PK, JL. Immune stainings: JV. Protein lysate arrays: RM. Wrote software packages, automated image analysis and structural classification: AH. Advanced statistical graphics: JPM. DNA and RNA expression analysis: MK. Gene set enrichment and gene ontology analysis, normalization and evaluation of mRNA microarray data, GEO (gene expression omnibus) submission: PK. Bioinformatics, supervising image processing and software development: JL. Scientific advise and infrastructure: OK.