A Mycobacterium tuberculosis Sigma Factor Network Responds to Cell-Envelope Damage by the Promising Anti-Mycobacterial Thioridazine

Noton K. Dutta; Smriti Mehra; Deepak Kaushal

doi:10.1371/journal.pone.0010069

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Peer-reviewed

Research Article

A Mycobacterium tuberculosis Sigma Factor Network Responds to Cell-Envelope Damage by the Promising Anti-Mycobacterial Thioridazine

Noton K. Dutta,

Affiliation Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana, United States of America
⨯
Smriti Mehra,

Affiliations Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana, United States of America, DNA Microarray and Expression Core, Tulane National Primate Research Center, Covington, Louisiana, United States of America
⨯
Deepak Kaushal

* E-mail: dkaushal@tulane.edu

Affiliations Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana, United States of America, DNA Microarray and Expression Core, Tulane National Primate Research Center, Covington, Louisiana, United States of America, Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, Louisiana, United States of America
⨯

A Mycobacterium tuberculosis Sigma Factor Network Responds to Cell-Envelope Damage by the Promising Anti-Mycobacterial Thioridazine

Noton K. Dutta,
Smriti Mehra,
Deepak Kaushal

Published: April 8, 2010
https://doi.org/10.1371/journal.pone.0010069

About the Authors

Noton K. Dutta

Affiliation Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana, United States of America

Smriti Mehra

Deepak Kaushal

* E-mail: dkaushal@tulane.edu

Affiliations Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana, United States of America, DNA Microarray and Expression Core, Tulane National Primate Research Center, Covington, Louisiana, United States of America, Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, Louisiana, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DK. Performed the experiments: NKD SM. Analyzed the data: NKD SM DK. Wrote the paper: DK.

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Mycobacterium tuberculosis
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Gene expression
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Integral membrane proteins
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