About the Authors

Virginia B. Kraus

Contributed equally to this work with: Virginia B. Kraus, Thomas B. Kepler

vbk@acpub.duke.edu

Affiliation Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

Thomas B. Kepler

Contributed equally to this work with: Virginia B. Kraus, Thomas B. Kepler

Affiliation Department of Biostatistics and Bioinformatics and Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

Thomas Stabler

Affiliation Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

Jordan Renner

Affiliation Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Joanne Jordan

Affiliation Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Competing Interests

This is an investigator initiated study funded by GlaxoSmithKline and the National Institutes of Health. The authors have no competing interests with respect to the commercial funder, including no employment, consultancy, patents, products in development or marketed products related to this work. The authors confirm that this does not alter their adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: VK JBR JMJ. Performed the experiments: TS JBR. Analyzed the data: TBK. Contributed reagents/materials/analysis tools: VK TBK JMJ. Wrote the paper: VK TBK. Supervised performance of the experiments: VK. Reviewed the paper: TS JBR JMJ.