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Research Article

Discovery of Novel MicroRNAs in Female Reproductive Tract Using Next Generation Sequencing

  • Chad J. Creighton equal contributor,

    equal contributor Contributed equally to this work with: Chad J. Creighton, Ashley L. Benham, Huifeng Zhu

    Affiliations: The Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, United States of America, Department of Medicine, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Ashley L. Benham equal contributor,

    equal contributor Contributed equally to this work with: Chad J. Creighton, Ashley L. Benham, Huifeng Zhu

    Affiliation: Department of Biology & Biochemistry, University of Houston, Houston, Texas, United States of America

    X
  • Huifeng Zhu equal contributor,

    equal contributor Contributed equally to this work with: Chad J. Creighton, Ashley L. Benham, Huifeng Zhu

    Affiliation: Department of Biology & Biochemistry, University of Houston, Houston, Texas, United States of America

    X
  • Mahjabeen F. Khan,

    Affiliation: Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Jeffrey G. Reid,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Ankur K. Nagaraja,

    Affiliations: Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Michael D. Fountain Jr,

    Affiliations: Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America, The Translational Biology and Molecular Medicine Program, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Olivia Dziadek,

    Affiliation: Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Derek Han,

    Affiliation: Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Lang Ma,

    Affiliation: Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Jong Kim,

    Affiliation: Department of Biology & Biochemistry, University of Houston, Houston, Texas, United States of America

    X
  • Shannon M. Hawkins ,

    Affiliation: Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, United States of America

    These authors also contributed equally to this work.

    X
  • Matthew L. Anderson ,

    Affiliations: Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, United States of America

    These authors also contributed equally to this work.

    X
  • Martin M. Matzuk ,

    Affiliations: Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America, The Translational Biology and Molecular Medicine Program, Baylor College of Medicine, Houston, Texas, United States of America

    These authors also contributed equally to this work.

    X
  • Preethi H. Gunaratne mail

    phgunaratne@uh.edu

    Affiliations: Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America, Department of Biology & Biochemistry, University of Houston, Houston, Texas, United States of America

    X
  • Published: March 10, 2010
  • DOI: 10.1371/journal.pone.0009637

About the Authors

Chad J. Creighton
The Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, United States of America
Chad J. Creighton
Department of Medicine, Baylor College of Medicine, Houston, Texas, United States of America
Mahjabeen F. Khan, Ankur K. Nagaraja, Michael D. Fountain Jr, Olivia Dziadek, Derek Han, Lang Ma, Matthew L. Anderson, Martin M. Matzuk, Preethi H. Gunaratne
Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America
Jeffrey G. Reid, Preethi H. Gunaratne
Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America
Ankur K. Nagaraja, Martin M. Matzuk
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
Martin M. Matzuk
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America
Ashley L. Benham, Huifeng Zhu, Jong Kim, Preethi H. Gunaratne
Department of Biology & Biochemistry, University of Houston, Houston, Texas, United States of America
Shannon M. Hawkins, Matthew L. Anderson
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, United States of America
Michael D. Fountain Jr, Martin M. Matzuk
The Translational Biology and Molecular Medicine Program, Baylor College of Medicine, Houston, Texas, United States of America

Corresponding Author

Email: phgunaratne@uh.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AN SH MA MMM PHG. Performed the experiments: AB HZ MK AN MF OD DH LM JK SH. Analyzed the data: CC AB HZ SH PHG. Contributed reagents/materials/analysis tools: CC HZ JR MA MMM PHG. Wrote the paper: CC AB HZ SH MA MMM PHG.