About the Authors
- Enrico Domenici
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* E-mail: enrico.h.domenici@gsk.com
Affiliation Neurosciences Centre of Excellence in Drug Discovery, GlaxoSmithKline R&D, Verona, Italy
- David R. Willé
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Affiliation Discovery Statistics Europe, GlaxoSmithKline R&D, Harlow, United Kingdom
- Federica Tozzi
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Affiliation Quantitative Sciences, GlaxoSmithKline R&D, Verona, Italy
- Inga Prokopenko
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Current address: Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
Affiliation Genetics Division, Drug Discovery, GlaxoSmithKline R&D, Verona, Italy
- Sam Miller
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Affiliation Discovery Statistics Europe, GlaxoSmithKline R&D, Harlow, United Kingdom
- Astrid McKeown
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Current address: Clinical Oncology MDC, GlaxoSmithKline R&D, Stockley Park, United Kingdom
Affiliation GSK Clinical Units, Addenbrooke's Hospital, Cambridge, United Kingdom
- Claire Brittain
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Affiliation Discovery Statistics Europe, GlaxoSmithKline R&D, Harlow, United Kingdom
- Dan Rujescu
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Affiliation Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Munich, Germany
- Ina Giegling
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Affiliation Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Munich, Germany
- Christoph W. Turck
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Affiliation Max-Planck Institute of Psychiatry, Munich, Germany
- Florian Holsboer
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Affiliation Max-Planck Institute of Psychiatry, Munich, Germany
- Edward T. Bullmore
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Affiliations GSK Clinical Units, Addenbrooke's Hospital, Cambridge, United Kingdom, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, United Kingdom
- Lefkos Middleton
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Current address: Division of Neurosciences and Mental Health, Imperial College, London, United Kingdom
Affiliation Genetics Division, Drug Discovery, GlaxoSmithKline R&D, Greenford, Middlesex, United Kingdom
- Emilio Merlo-Pich
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Affiliation Neurosciences Centre of Excellence in Drug Discovery, GlaxoSmithKline R&D, Verona, Italy
- Robert C. Alexander
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Affiliation Neurosciences Centre of Excellence in Drug Discovery, GlaxoSmithKline R&D, Verona, Italy
- Pierandrea Muglia
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Current address: Department of Psychiatry, University of Toronto, Toronto, Canada; NeuroSearch A/S, Ballerup, Denmark
Affiliation Neurosciences Centre of Excellence in Drug Discovery, GlaxoSmithKline R&D, Verona, Italy
Competing Interests
ED, DW, FT, SM, AMK, EMP and RA are currently full-time employees at GSK. ETB is employed part-time at GSK and part-time at the University of Cambridge. The authors agree with the PLoS ONE data and materials sharing policy.
Author Contributions
Conceived and designed the experiments: ED FT IP LTM EMP PM. Analyzed the data: ED DRW IP SM AM CB CWT EB EMP RCA PM. Contributed reagents/materials/analysis tools: AM DR IG FH. Wrote the paper: ED DRW PM. Critically reviewed the manuscript: FT DR IG CWT FH EB LTM EMP RCA. Contributed text to the final manuscript: SM CB.