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Research Article

Murine Features of Neurogenesis in the Human Hippocampus across the Lifespan from 0 to 100 Years

  • Rolf Knoth,

    Affiliation: Department of Neuropathology, University of Freiburg, Freiburg, Germany

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  • Ilyas Singec,

    Affiliations: Department of Neuropathology, University of Freiburg, Freiburg, Germany, Burnham Institute for Medical Research, Stem Cell and Regeneration Program, La Jolla, California, United States of America

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  • Margarethe Ditter,

    Affiliation: Department of Neuropathology, University of Freiburg, Freiburg, Germany

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  • Georgios Pantazis,

    Affiliation: Department of Neuropathology, University of Freiburg, Freiburg, Germany

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  • Philipp Capetian,

    Affiliations: Department of Neuropathology, University of Freiburg, Freiburg, Germany, Laboratory of Molecular Neurosurgery, Department of Stereotactic and Functional Neurosurgery, University of Freiburg, Freiburg, Germany

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  • Ralf P. Meyer,

    Affiliation: Department of Neuropathology, University of Freiburg, Freiburg, Germany

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  • Volker Horvat,

    Affiliation: CRTD – Center for Regenerative Therapies Dresden, Dresden, Germany

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  • Benedikt Volk,

    Affiliation: Department of Neuropathology, University of Freiburg, Freiburg, Germany

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  • Gerd Kempermann mail

    gerd.kempermann@crt-dresden.de

    Affiliation: CRTD – Center for Regenerative Therapies Dresden, Dresden, Germany

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  • Published: January 29, 2010
  • DOI: 10.1371/journal.pone.0008809

About the Authors

Rolf Knoth, Ilyas Singec, Margarethe Ditter, Georgios Pantazis, Philipp Capetian, Ralf P. Meyer, Benedikt Volk
Department of Neuropathology, University of Freiburg, Freiburg, Germany
Ilyas Singec
Burnham Institute for Medical Research, Stem Cell and Regeneration Program, La Jolla, California, United States of America
Philipp Capetian
Laboratory of Molecular Neurosurgery, Department of Stereotactic and Functional Neurosurgery, University of Freiburg, Freiburg, Germany
Volker Horvat, Gerd Kempermann
CRTD – Center for Regenerative Therapies Dresden, Dresden, Germany

Corresponding Author

Email: gerd.kempermann@crt-dresden.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RK IS RPM GK. Performed the experiments: RK IS MD GP PC RPM VH. Analyzed the data: RK IS GP PC RPM BV GK. Contributed reagents/materials/analysis tools: RK MD GP RPM VH BV. Wrote the paper: RK RPM GK.