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Research Article

Genomic Profiling of Messenger RNAs and MicroRNAs Reveals Potential Mechanisms of TWEAK-Induced Skeletal Muscle Wasting in Mice

  • Siva K. Panguluri equal contributor,

    equal contributor Contributed equally to this work with: Siva K. Panguluri, Shephali Bhatnagar

    Affiliation: Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky, United States of America

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  • Shephali Bhatnagar equal contributor,

    equal contributor Contributed equally to this work with: Siva K. Panguluri, Shephali Bhatnagar

    Affiliation: Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky, United States of America

    X
  • Akhilesh Kumar,

    Affiliation: Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky, United States of America

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  • John J. McCarthy,

    Affiliation: Department of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

    X
  • Apurva K. Srivastava,

    Affiliation: Laboratory of Human Toxicology and Pharmacology, Applied & Developmental Research Directorate SAIC-Frederick, National Cancer Institute, Frederick, Maryland, United States of America

    X
  • Nigel G. Cooper,

    Affiliation: Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky, United States of America

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  • Robert F. Lundy,

    Affiliation: Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky, United States of America

    X
  • Ashok Kumar mail

    ashok.kumar@louisville.edu

    Affiliation: Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky, United States of America

    X
  • Published: January 19, 2010
  • DOI: 10.1371/journal.pone.0008760

About the Authors

Siva K. Panguluri, Shephali Bhatnagar, Akhilesh Kumar, Nigel G. Cooper, Robert F. Lundy, Ashok Kumar
Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky, United States of America
John J. McCarthy
Department of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America
Apurva K. Srivastava
Laboratory of Human Toxicology and Pharmacology, Applied & Developmental Research Directorate SAIC-Frederick, National Cancer Institute, Frederick, Maryland, United States of America

Corresponding Author

Email: ashok.kumar@louisville.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SKP NGC RFL AK. Performed the experiments: SKP SB AK. Analyzed the data: SKP SB AKS NGC RFL AK. Contributed reagents/materials/analysis tools: JJM. Wrote the paper: SKP SB AK.