About the Authors

Tohru Hasegawa

hasegawa@yumekobo-shizuka.com

Affiliation Saga Women's Junior College, Saga City, Saga, Japan

Nobuyuki Mikoda

Affiliation Kyudo Ltd., Tosu City, Saga, Japan

Masashi Kitazawa

Affiliation Department of Neurobiology & Behavior, University of California Irvine, Irvine, California, United States of America

Frank M. LaFerla

Affiliation Department of Neurobiology & Behavior, University of California Irvine, Irvine, California, United States of America

Competing Interests

N.M. is employed by Kyudo Ltd; this company had no role in this study design, data collection and analysis, decision to publish, or preparation of this manuscript. All other authors declare no competing interests. Parts of the experiment, such as feeding model mice, were supported by Arfresa Pharmcology (http://www.alfresa-pharma.co.jp/).

Author Contributions

Conceived and designed the experiments: TH. Performed the experiments: TH NM. Analyzed the data: TH. Contributed reagents/materials/analysis tools: TH MK. Wrote the paper: TH. Discussion and development of 3xTg-AD model mice: FML.