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Research Article

Inducible Nucleosome Depletion at OREBP-Binding-Sites by Hypertonic Stress

  • Edith H. Y. Tong equal contributor,

    equal contributor Contributed equally to this work with: Edith H. Y. Tong, Jin-Jun Guo

    Affiliations: Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, China, State Key Laboratory in Oncology in South China, The Chinese University of Hong Kong, Hong Kong, China, Department of Physiology, The University of Hong Kong, Hong Kong, China

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  • Jin-Jun Guo equal contributor,

    equal contributor Contributed equally to this work with: Edith H. Y. Tong, Jin-Jun Guo

    Affiliation: Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Institute of Viral Hepatitis, Chongqing University of Medical Sciences, Chong Qing, China

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  • Song-Xiao Xu,

    Affiliations: Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, China, State Key Laboratory in Oncology in South China, The Chinese University of Hong Kong, Hong Kong, China

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  • Keri Mak,

    Affiliation: Department of Anatomy, The University of Hong Kong, Hong Kong, China

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  • Sookja K. Chung,

    Affiliation: Department of Anatomy, The University of Hong Kong, Hong Kong, China

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  • Stephen S. M. Chung,

    Affiliation: Department of Physiology, The University of Hong Kong, Hong Kong, China

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  • Ali-Long Huang,

    Affiliation: Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Institute of Viral Hepatitis, Chongqing University of Medical Sciences, Chong Qing, China

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  • Ben C. B. Ko mail

    benko@cuhk.edu.hk

    Affiliations: Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, China, State Key Laboratory in Oncology in South China, The Chinese University of Hong Kong, Hong Kong, China

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  • Published: December 24, 2009
  • DOI: 10.1371/journal.pone.0008435

About the Authors

Edith H. Y. Tong, Song-Xiao Xu, Ben C. B. Ko
Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, China
Edith H. Y. Tong, Song-Xiao Xu, Ben C. B. Ko
State Key Laboratory in Oncology in South China, The Chinese University of Hong Kong, Hong Kong, China
Jin-Jun Guo, Ali-Long Huang
Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Institute of Viral Hepatitis, Chongqing University of Medical Sciences, Chong Qing, China
Keri Mak, Sookja K. Chung
Department of Anatomy, The University of Hong Kong, Hong Kong, China
Edith H. Y. Tong, Stephen S. M. Chung
Department of Physiology, The University of Hong Kong, Hong Kong, China

Corresponding Author

Email: benko@cuhk.edu.hk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BK. Performed the experiments: EHYT JJG SXX KM. Analyzed the data: EHYT JJG SXX BK. Contributed reagents/materials/analysis tools: SKC SSMC ALH. Wrote the paper: BK.