About the Authors

Philippe Noriel Q. Pascua

Affiliation College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea

Min-Suk Song

Affiliation College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea

Jun Han Lee

Affiliation College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea

Kuk Jin Park

Affiliation College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea

Hyeok-il Kwon

Affiliation College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea

Yun Hee Baek

Affiliation College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea

Seung-Pyo Hong

Affiliation Bioleaders Corporation, Daejeon, Republic of Korea

Jong-Bok Rho

Affiliation Bioleaders Corporation, Daejeon, Republic of Korea

Chul-Joong Kim

Affiliation College of Veterinary Medicine, Chungnam National University, DaeJeon, Republic of Korea

Haryoung Poo

Affiliation Korean Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea

Thomas S. Ryoo

Affiliation Prestige World Genetics, Genetics Korea, Ltd., Pyongtaek, Republic of Korea

Moon-Hee Sung

Affiliation Bioleaders Corporation, Daejeon, Republic of Korea

Young Ki Choi

choiki55@chungbuk.ac.kr

Affiliation College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea

Competing Interests

Thomas S. Ryoo is an employee of Prestige World Genetics, Genetics Korea, Ltd., which provided the specific-pathogen-free miniature pigs. Moon-Hee Sung is CEO of a commercial company, Bioleaders Corporation. In addition, he is a Professor at the Kookmin University in Seoul, Republic of Korea. However, these co-authors declare that they do not have any financial, personal, or professional interests with regards to the submitted work. Thus, authors confirm that such affiliations do not alter their adherence to all the PLoS ONE policies on sharing data and materials (as detailed online: http://www.plosone.org/static/policies.action).

Author Contributions

Conceived and designed the experiments: PNQP MSS CJK YKC. Performed the experiments: PNQP MSS JHL KJP HiK YHB SpH JBR YKC. Analyzed the data: PNQP MSS CJK YKC. Contributed reagents/materials/analysis tools: SpH HP TSR MHS YKC. Wrote the paper: PNQP MSS YKC.