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Research Article

Signature-Tagged Mutagenesis in a Chicken Infection Model Leads to the Identification of a Novel Avian Pathogenic Escherichia coli Fimbrial Adhesin

  • Esther-Maria Antão mail,

    antao.em@vetmed.fu-berlin.de

    Affiliation: Institut für Mikrobiologie und Tierseuchen, Freie Universität Berlin, Berlin, Germany

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  • Christa Ewers,

    Affiliation: Institut für Mikrobiologie und Tierseuchen, Freie Universität Berlin, Berlin, Germany

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  • Doreen Gürlebeck,

    Affiliation: Institut für Mikrobiologie und Tierseuchen, Freie Universität Berlin, Berlin, Germany

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  • Rudolf Preisinger,

    Affiliation: Lohmann Tierzucht GmbH, Cuxhaven, Germany

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  • Timo Homeier,

    Affiliations: Institut für Mikrobiologie und Tierseuchen, Freie Universität Berlin, Berlin, Germany, Institute of Animal Hygiene and Veterinary Public Health, Veterinary Faculty, Universität Leipzig, Leipzig, Germany

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  • Ganwu Li,

    Affiliation: Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America

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  • Lothar H. Wieler

    Affiliation: Institut für Mikrobiologie und Tierseuchen, Freie Universität Berlin, Berlin, Germany

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  • Published: November 12, 2009
  • DOI: 10.1371/journal.pone.0007796

About the Authors

Esther-Maria Antão, Christa Ewers, Doreen Gürlebeck, Timo Homeier, Lothar H. Wieler
Institut für Mikrobiologie und Tierseuchen, Freie Universität Berlin, Berlin, Germany
Rudolf Preisinger
Lohmann Tierzucht GmbH, Cuxhaven, Germany
Ganwu Li
Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America
Timo Homeier
Institute of Animal Hygiene and Veterinary Public Health, Veterinary Faculty, Universität Leipzig, Leipzig, Germany

Corresponding Author

Email: antao.em@vetmed.fu-berlin.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EMA CE DG GL LHW. Performed the experiments: EMA. Analyzed the data: EMA CE TH. Contributed reagents/materials/analysis tools: RP. Wrote the paper: EMA. Initiated the study and project: RP LHW.