About the Authors

Joanna Doumanis

Affiliation Lab for Structural Neuropathology, RIKEN Brain Science Institute, Wako, Saitama, Japan

Koji Wada

Affiliation Lab for Structural Neuropathology, RIKEN Brain Science Institute, Wako, Saitama, Japan

Yoshihiro Kino

Affiliation Lab for Structural Neuropathology, RIKEN Brain Science Institute, Wako, Saitama, Japan

Adrian W. Moore

Affiliation Moore Research Unit, RIKEN Brain Science Institute, Wako, Saitama, Japan

Nobuyuki Nukina

nukina@brain.riken.jp

Affiliation Lab for Structural Neuropathology, RIKEN Brain Science Institute, Wako, Saitama, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JD NN. Performed the experiments: JD KW. Analyzed the data: JD YK. Contributed reagents/materials/analysis tools: JD KW AWM. Wrote the paper: JD NN. Discussions and project supervision: NN. The design and implementation of the experiments including establishment of cell culture and in vivo models: JD. Carrying out the RNAi high-throughput screen, data analysis, cell treatments, microscopy, de novo probe design and all in vivo experiments: JD. Synthesis and purification of dsRNAs, Western blot analysis, and RTPCR: KW. Analysis the functional roles of selected candidates and other data: YK. Support of Fly maintenance materials and facilities: AWM.