About the Authors
- Patrice Dubreuil
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* E-mail: patrice.dubreuil@inserm.fr (PD); olivier.hermine@nck.aphp.fr (OH)
Affiliations INSERM, U891, Centre de Recherche en Cancérologie de Marseille, Signalisation, Hematopoiesis and Mechanisms of Oncogenesis, Centre de référence des mastocytoses, Marseille, France, Institut Paoli-Calmettes, Marseille, France, Univ Méditerranée, Marseille, France, AB Science SA, Paris, France
- Sébastien Letard
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Affiliations INSERM, U891, Centre de Recherche en Cancérologie de Marseille, Signalisation, Hematopoiesis and Mechanisms of Oncogenesis, Centre de référence des mastocytoses, Marseille, France, Institut Paoli-Calmettes, Marseille, France, Univ Méditerranée, Marseille, France, AB Science SA, Paris, France
- Marco Ciufolini
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Affiliations AB Science SA, Paris, France, University of British Columbia, Department of Chemistry, Vancouver, British Columbia, Canada
- Laurent Gros
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Affiliation AB Science SA, Paris, France
- Martine Humbert
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Affiliation AB Science SA, Paris, France
- Nathalie Castéran
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Affiliation AB Science SA, Paris, France
- Laurence Borge
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Affiliations INSERM, U891, Centre de Recherche en Cancérologie de Marseille, Signalisation, Hematopoiesis and Mechanisms of Oncogenesis, Centre de référence des mastocytoses, Marseille, France, Institut Paoli-Calmettes, Marseille, France, Univ Méditerranée, Marseille, France
- Bérengère Hajem
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Affiliation AB Science SA, Paris, France
- Anne Lermet
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Affiliation AB Science SA, Paris, France
- Wolfgang Sippl
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Affiliation Institute of Pharmaceutical Chemistry, Martin-Luther-Universität, Halle, Wittenberg, Germany
- Edwige Voisset
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Affiliations INSERM, U891, Centre de Recherche en Cancérologie de Marseille, Signalisation, Hematopoiesis and Mechanisms of Oncogenesis, Centre de référence des mastocytoses, Marseille, France, Institut Paoli-Calmettes, Marseille, France, Univ Méditerranée, Marseille, France
- Michel Arock
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Affiliation Laboratory of Oncology and Molecular Pharmacology, CNRS, UMR 8113, Ecole Normale Supérieure de Cachan, Cachan, France
- Christian Auclair
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Affiliations AB Science SA, Paris, France, Laboratory of Oncology and Molecular Pharmacology, CNRS, UMR 8113, Ecole Normale Supérieure de Cachan, Cachan, France
- Phillip S. Leventhal
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Affiliation AB Science SA, Paris, France
- Colin D. Mansfield
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Affiliation AB Science SA, Paris, France
- Alain Moussy
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Affiliation AB Science SA, Paris, France
- Olivier Hermine
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* E-mail: patrice.dubreuil@inserm.fr (PD); olivier.hermine@nck.aphp.fr (OH)
Affiliations AB Science SA, Paris, France, Service d'Hematologie, CNRS, UMR 8147, Centre de référence des mastocytoses, Université Paris V René Descartes, Hôpital Necker, Paris, France
Competing Interests
This study was financially supported by AB Science, S.A., Paris, France. AB Science is the proprietary holder of masitinib. Masitinib is under clinical development by AB Science. P.D., S.L., M.C., L.G., M.H., N.C., B.H., A.L., C.A., P.S.L., C.D.M. and A.M. are employees of the study sponsor, AB Science. M.C., M.A. and O.H. are scientific advisors to the study sponsor, AB Science. P.D., M.C., L.G., M.H., A.L., A.M. and O.H. are shareholders of the study sponsor, AB Science. M.C., A.L. and A.M. are applicants on numerous patents pertaining to masitinib.
Author Contributions
Conceived and designed the experiments: PD MC LG MH AL MA CA OH. Performed the experiments: PD SL MC LG MH NC LB BH AL WS EV MA CA. Analyzed the data: PD MC LG MH NC BH AL WS MA CA PL CM AM OH. Wrote the paper: PD LG PL CM AM OH.