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Research Article

Zebrafish IGF Genes: Gene Duplication, Conservation and Divergence, and Novel Roles in Midline and Notochord Development

  • Shuming Zou,

    Affiliations: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America, Key Laboratory of Aquatic Genetic Resources, Shanghai Ocean University, Shanghai, China

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  • Hiroyasu Kamei,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Zubin Modi,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Cunming Duan mail

    cduan@umich.edu

    Affiliations: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America, Laboratory of Molecular Medicine, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China

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  • Published: September 17, 2009
  • DOI: 10.1371/journal.pone.0007026

About the Authors

Shuming Zou, Hiroyasu Kamei, Zubin Modi, Cunming Duan
Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America
Shuming Zou
Key Laboratory of Aquatic Genetic Resources, Shanghai Ocean University, Shanghai, China
Cunming Duan
Laboratory of Molecular Medicine, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China

Corresponding Author

Email: cduan@umich.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CD. Performed the experiments: SZ HK ZM. Analyzed the data: SZ HK CD. Wrote the paper: SZ CD.