GWAS Meets Microarray: Are the Results of Genome-Wide Association Studies and Gene-Expression Profiling Consistent? Prostate Cancer as an Example

Ivan P. Gorlov; Gary E. Gallick; Olga Y. Gorlova; Christopher Amos; Christopher J. Logothetis

doi:10.1371/journal.pone.0006511

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Open Access

Peer-reviewed

Research Article

GWAS Meets Microarray: Are the Results of Genome-Wide Association Studies and Gene-Expression Profiling Consistent? Prostate Cancer as an Example

Ivan P. Gorlov ,

* E-mail: ipgorlov@mdanderson.org

Affiliation Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Gary E. Gallick,

Affiliation Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Olga Y. Gorlova,

Affiliation Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Christopher Amos,

Affiliation Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Christopher J. Logothetis

Affiliation Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯

GWAS Meets Microarray: Are the Results of Genome-Wide Association Studies and Gene-Expression Profiling Consistent? Prostate Cancer as an Example

Ivan P. Gorlov,
Gary E. Gallick,
Olga Y. Gorlova,
Christopher Amos,
Christopher J. Logothetis

Published: August 4, 2009
https://doi.org/10.1371/journal.pone.0006511

About the Authors

Ivan P. Gorlov

* E-mail: ipgorlov@mdanderson.org

Affiliation Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Gary E. Gallick

Affiliation Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Olga Y. Gorlova

Affiliation Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Christopher Amos

Affiliation Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Christopher J. Logothetis

Affiliation Department of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: IPG OYG CL. Performed the experiments: IPG CIA. Analyzed the data: IPG GG OYG. Wrote the paper: IPG GG CIA CL.

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Prostate cancer
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Genome-wide association studies
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Microarrays
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Cell adhesion
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Gene expression
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Prostate gland
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Metaanalysis
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Single nucleotide polymorphisms
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