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Research Article

Cytoprotective Nrf2 Pathway Is Induced In Chronically Txnrd 1-Deficient Hepatocytes

  • Elena S. Suvorova,

    Affiliation: Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America

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  • Olivier Lucas,

    Affiliation: Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America

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  • Carla M. Weisend,

    Affiliation: Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America

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  • MaryClare F. Rollins,

    Affiliation: Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America

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  • Gary F. Merrill,

    Affiliation: Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon, United States of America

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  • Mario R. Capecchi,

    Affiliation: Howard Hughes Medical Institute (HHMI), University of Utah, Salt Lake City, Utah, United States of America

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  • Edward E. Schmidt mail

    eschmidt@montana.edu

    Affiliations: Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America, Center for Reproductive Biology, Washington State University, Pullman, Washington, United States of America

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  • Published: July 07, 2009
  • DOI: 10.1371/journal.pone.0006158

About the Authors

Elena S. Suvorova, Olivier Lucas, Carla M. Weisend, MaryClare F. Rollins, Edward E. Schmidt
Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
Gary F. Merrill
Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon, United States of America
Mario R. Capecchi
Howard Hughes Medical Institute (HHMI), University of Utah, Salt Lake City, Utah, United States of America
Edward E. Schmidt
Center for Reproductive Biology, Washington State University, Pullman, Washington, United States of America

Corresponding Author

Email: eschmidt@montana.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ESS EES. Performed the experiments: ESS CMW MFR EES. Analyzed the data: ESS OL EES. Contributed reagents/materials/analysis tools: GM MRC EES. Wrote the paper: ESS EES.