About the Authors

Sally H. Vitali

Affiliation Division of Critical Care Medicine, Children's Hospital Boston, Boston, Massachusetts, United States of America

S. Alex Mitsialis

Affiliation Division of Newborn Medicine, Children's Hospital Boston, Boston, Massachusetts, United States of America

Olin D. Liang

Affiliation Division of Newborn Medicine, Children's Hospital Boston, Boston, Massachusetts, United States of America

Xiaoli Liu

Affiliation Pulmonary Division, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Angeles Fernandez-Gonzalez

Affiliation Division of Newborn Medicine, Children's Hospital Boston, Boston, Massachusetts, United States of America

Helen Christou

Affiliation Division of Newborn Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Xinqi Wu

Affiliation Division of Newborn Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Francis X. McGowan

Affiliation Division of Cardiac Anesthesia, Children's Hospital Boston, Boston, Massachusetts, United States of America

Stella Kourembanas

stella.kourembanas@childrens.harvard.edu

Affiliation Division of Newborn Medicine, Children's Hospital Boston, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Performed the experiments: SV. Wrote the paper: SV. PI of laboratory, provided overall scientific direction and funded the research: SK. Edited the manuscript: SK SAM HC. Performed all animal experiments, cardiomyocyte work, proliferation studies: SV. Provided intellectual input, maintained HO-1 null line, engineered hypoxia chamber setup and software control, and taught several animal techniques to Dr. Vitali: SAM. Performed right ventricular pressure measurements for several experiments: ODL XL. Taught Dr. Vitali histological techniques and lung inflation: AFG. Analyzed pulmonary arteriolar remodeling: HC. Performed smooth muscle cell migration experiments: XW. Cardiac anesthesiologist who directed cardiomyocyte experiments: FXM.