About the Authors

Linda C. Enns

Affiliation Departments of Comparative Medicine, Biostatistics, Pharmacology, and Pathology, School of Medicine, University of Washington, Seattle, Washington, United States of America

John F. Morton

Affiliation Departments of Comparative Medicine, Biostatistics, Pharmacology, and Pathology, School of Medicine, University of Washington, Seattle, Washington, United States of America

Piper R. Treuting

Affiliation Departments of Comparative Medicine, Biostatistics, Pharmacology, and Pathology, School of Medicine, University of Washington, Seattle, Washington, United States of America

Mary J. Emond

Affiliation Departments of Comparative Medicine, Biostatistics, Pharmacology, and Pathology, School of Medicine, University of Washington, Seattle, Washington, United States of America

Norman S. Wolf

Affiliation Departments of Comparative Medicine, Biostatistics, Pharmacology, and Pathology, School of Medicine, University of Washington, Seattle, Washington, United States of America

G. S. McKnight

Affiliation Departments of Comparative Medicine, Biostatistics, Pharmacology, and Pathology, School of Medicine, University of Washington, Seattle, Washington, United States of America

Peter S. Rabinovitch

Affiliation Departments of Comparative Medicine, Biostatistics, Pharmacology, and Pathology, School of Medicine, University of Washington, Seattle, Washington, United States of America

Warren C. Ladiges

wladiges@u.washington.edu

Affiliation Departments of Comparative Medicine, Biostatistics, Pharmacology, and Pathology, School of Medicine, University of Washington, Seattle, Washington, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WL. Performed the experiments: LCE JFM PRT. Analyzed the data: LCE PRT MJE WL. Contributed reagents/materials/analysis tools: NSW GSM PSR WL. Wrote the paper: LCE.