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Research Article

Intraluminal Blockade of Cell-Surface CD74 and Glucose Regulated Protein 78 Prevents Substance P-Induced Bladder Inflammatory Changes in the Rat

  • Pedro L. Vera mail,

    pvera@health.usf.edu

    Affiliations: The Bay Pines VA Healthcare System, Research & Development, Bay Pines, Florida, United States of America, Department of Surgery, Division of Urology, University of South Florida, College of Medicine, Tampa, Florida, United States of America

    X
  • Xihai Wang,

    Affiliations: The Bay Pines VA Healthcare System, Research & Development, Bay Pines, Florida, United States of America, Department of Surgery, Division of Urology, University of South Florida, College of Medicine, Tampa, Florida, United States of America

    X
  • Richard J. Bucala,

    Affiliation: Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America

    X
  • Katherine L. Meyer-Siegler

    Affiliations: The Bay Pines VA Healthcare System, Research & Development, Bay Pines, Florida, United States of America, Department of Molecular Medicine, University of South Florida, College of Medicine, Tampa, Florida, United States of America

    X
  • Published: June 08, 2009
  • DOI: 10.1371/journal.pone.0005835

About the Authors

Pedro L. Vera, Xihai Wang, Katherine L. Meyer-Siegler
The Bay Pines VA Healthcare System, Research & Development, Bay Pines, Florida, United States of America
Pedro L. Vera, Xihai Wang
Department of Surgery, Division of Urology, University of South Florida, College of Medicine, Tampa, Florida, United States of America
Richard J. Bucala
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
Katherine L. Meyer-Siegler
Department of Molecular Medicine, University of South Florida, College of Medicine, Tampa, Florida, United States of America

Corresponding Author

Email: pvera@health.usf.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PLLV KLMS. Performed the experiments: PLLV XW KLMS. Analyzed the data: PLLV XW RB KLMS. Contributed reagents/materials/analysis tools: PLLV KLMS. Wrote the paper: PLLV XW RB KLMS.