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Research Article

IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin

  • Ali Khoshnan mail,

    khoshnan@caltech.edu

    Affiliation: Biology Division 216-76, California Institute of Technology, Pasadena, California, United States of America

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  • Jan Ko,

    Affiliation: Biology Division 216-76, California Institute of Technology, Pasadena, California, United States of America

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  • Simona Tescu,

    Affiliation: Biology Division 216-76, California Institute of Technology, Pasadena, California, United States of America

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  • Patrick Brundin,

    Affiliation: Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund, Sweden

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  • Paul H. Patterson

    Affiliation: Biology Division 216-76, California Institute of Technology, Pasadena, California, United States of America

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  • Published: June 02, 2009
  • DOI: 10.1371/journal.pone.0005768

About the Authors

Ali Khoshnan, Jan Ko, Simona Tescu, Paul H. Patterson
Biology Division 216-76, California Institute of Technology, Pasadena, California, United States of America
Patrick Brundin
Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund, Sweden

Corresponding Author

Email: khoshnan@caltech.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AK. Performed the experiments: AK ST. Analyzed the data: AK JK PHP. Contributed reagents/materials/analysis tools: PB. Wrote the paper: AK PHP.