Dazl Functions in Maintenance of Pluripotency and Genetic and Epigenetic Programs of Differentiation in Mouse Primordial Germ Cells In Vivo and In Vitro

Kelly M. Haston; Joyce Y. Tung; Renee A. Reijo Pera

doi:10.1371/journal.pone.0005654

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Open Access

Peer-reviewed

Research Article

Dazl Functions in Maintenance of Pluripotency and Genetic and Epigenetic Programs of Differentiation in Mouse Primordial Germ Cells In Vivo and In Vitro

Kelly M. Haston,

Affiliation Institute for Stem Cell Biology & Regenerative Medicine, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, California, United States of America
⨯
Joyce Y. Tung,

Affiliation Institute for Stem Cell Biology & Regenerative Medicine, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, California, United States of America
⨯
Renee A. Reijo Pera

* E-mail: reneer@stanford.edu

Affiliation Institute for Stem Cell Biology & Regenerative Medicine, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, California, United States of America
⨯

Dazl Functions in Maintenance of Pluripotency and Genetic and Epigenetic Programs of Differentiation in Mouse Primordial Germ Cells In Vivo and In Vitro

Kelly M. Haston,
Joyce Y. Tung,
Renee A. Reijo Pera

Published: May 21, 2009
https://doi.org/10.1371/journal.pone.0005654

About the Authors

Kelly M. Haston

Affiliation Institute for Stem Cell Biology & Regenerative Medicine, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, California, United States of America

Joyce Y. Tung

Affiliation Institute for Stem Cell Biology & Regenerative Medicine, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, California, United States of America

Renee A. Reijo Pera

* E-mail: reneer@stanford.edu

Affiliation Institute for Stem Cell Biology & Regenerative Medicine, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KMH JT RARP. Performed the experiments: KMH JT. Analyzed the data: KMH JT. Wrote the paper: KMH JT RARP.

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Germ cells
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Cell differentiation
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Heterozygosity
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DNA methylation
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Gene expression
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Gonads
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Pluripotency
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Methylation
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