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Research Article

Genome-Wide Massively Parallel Sequencing of Formaldehyde Fixed-Paraffin Embedded (FFPE) Tumor Tissues for Copy-Number- and Mutation-Analysis

  • Michal R. Schweiger mail,

    mschweig@molgen.mpg.de

    Affiliations: Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany, Institute for Medical Genetics, Charité Universitätsmedizin, Berlin, Germany

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  • Martin Kerick,

    Affiliation: Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany

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  • Bernd Timmermann,

    Affiliation: Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany

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  • Marcus W. Albrecht,

    Affiliation: Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany

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  • Tatjana Borodina,

    Affiliation: Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany

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  • Dmitri Parkhomchuk,

    Affiliation: Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany

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  • Kurt Zatloukal,

    Affiliation: Institute of Pathology, Medical University, Graz, Austria

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  • Hans Lehrach

    Affiliation: Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany

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  • Published: May 14, 2009
  • DOI: 10.1371/journal.pone.0005548

About the Authors

Michal R. Schweiger, Martin Kerick, Bernd Timmermann, Marcus W. Albrecht, Tatjana Borodina, Dmitri Parkhomchuk, Hans Lehrach
Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany
Michal R. Schweiger
Institute for Medical Genetics, Charité Universitätsmedizin, Berlin, Germany
Kurt Zatloukal
Institute of Pathology, Medical University, Graz, Austria

Corresponding Author

Email: mschweig@molgen.mpg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MRS KZ HL. Performed the experiments: MRS BT TB. Analyzed the data: MRS MK BT MWA DP KZ HL. Contributed reagents/materials/analysis tools: MRS MK BT MWA TB DP KZ HL. Wrote the paper: MRS MK KZ.