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Research Article

A Top-Down Approach to Infer and Compare Domain-Domain Interactions across Eight Model Organisms

  • Chittibabu Guda mail,

    cguda@albany.edu

    Affiliation: GenNYsis Center for Excellence in Cancer Genomics and Department of Epidemiology & Biostatistics, State University of New York at Albany, Rensselaer, New York, United States of America

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  • Brian R. King,

    Affiliations: GenNYsis Center for Excellence in Cancer Genomics and Department of Epidemiology & Biostatistics, State University of New York at Albany, Rensselaer, New York, United States of America, Department of Computer Information Science, Mansfield University, Mansfield, Pennsylvania, United States of America

    X
  • Lipika R. Pal,

    Affiliations: GenNYsis Center for Excellence in Cancer Genomics and Department of Epidemiology & Biostatistics, State University of New York at Albany, Rensselaer, New York, United States of America, Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, Maryland, United States of America

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  • Purnima Guda

    Affiliation: GenNYsis Center for Excellence in Cancer Genomics and Department of Epidemiology & Biostatistics, State University of New York at Albany, Rensselaer, New York, United States of America

    X
  • Published: March 31, 2009
  • DOI: 10.1371/journal.pone.0005096

About the Authors

Chittibabu Guda, Brian R. King, Lipika R. Pal, Purnima Guda
GenNYsis Center for Excellence in Cancer Genomics and Department of Epidemiology & Biostatistics, State University of New York at Albany, Rensselaer, New York, United States of America
Brian R. King
Department of Computer Information Science, Mansfield University, Mansfield, Pennsylvania, United States of America
Lipika R. Pal
Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, Maryland, United States of America

Corresponding Author

Email: cguda@albany.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CG BRK. Performed the experiments: CG BRK LRP PG. Analyzed the data: CG BRK LRP PG. Wrote the paper: CG BRK.