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Research Article

Conservation of Carbohydrate Binding Interfaces — Evidence of Human HBGA Selection in Norovirus Evolution

  • Ming Tan equal contributor,

    equal contributor Contributed equally to this work with: Ming Tan, Ming Xia

    Affiliations: Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

    X
  • Ming Xia equal contributor,

    equal contributor Contributed equally to this work with: Ming Tan, Ming Xia

    Affiliation: Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

    X
  • Yutao Chen,

    Affiliation: National Laboratory of Bio macromolecules, Institute of Biophysics, Chinese Academy of Science, Beijing, China

    X
  • Weiming Bu,

    Affiliation: Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

    X
  • Rashmi S. Hegde,

    Affiliations: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

    X
  • Jarek Meller,

    Affiliations: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

    X
  • Xuemei Li,

    Affiliation: National Laboratory of Bio macromolecules, Institute of Biophysics, Chinese Academy of Science, Beijing, China

    X
  • Xi Jiang mail

    jason.jiang@cchmc.org

    Affiliations: Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

    X
  • Published: April 01, 2009
  • DOI: 10.1371/journal.pone.0005058

About the Authors

Ming Tan, Ming Xia, Xi Jiang
Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
Ming Tan, Rashmi S. Hegde, Jarek Meller, Xi Jiang
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
Weiming Bu, Rashmi S. Hegde
Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
Jarek Meller
Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
Yutao Chen, Xuemei Li
National Laboratory of Bio macromolecules, Institute of Biophysics, Chinese Academy of Science, Beijing, China

Corresponding Author

Email: jason.jiang@cchmc.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MT XJ. Performed the experiments: MT MX. Analyzed the data: MT MX YC WB RH JM XL. Contributed reagents/materials/analysis tools: MT RH JM. Wrote the paper: MT MX XJ.