About the Authors

Katrina Steiling

steiling@bu.edu

Affiliations The Pulmonary Center, Boston University Medical Center, Boston, Massachusetts, United States of America, Bioinformatics Program, College of Engineering, Boston University, Boston, Massachusetts, United States of America

Aran Y. Kadar

Affiliation Newton-Wellesley Hospital, Newton, Massachusetts, United States of America

Agnes Bergerat

Affiliation Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

James Flanigon

Affiliation Bioinformatics Program, College of Engineering, Boston University, Boston, Massachusetts, United States of America

Sriram Sridhar

Affiliation Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

Vishal Shah

Affiliation Bioinformatics Program, College of Engineering, Boston University, Boston, Massachusetts, United States of America

Q. Rushdy Ahmad

Affiliation The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

Jerome S. Brody

Affiliation The Pulmonary Center, Boston University Medical Center, Boston, Massachusetts, United States of America

Marc E. Lenburg

Affiliations The Pulmonary Center, Boston University Medical Center, Boston, Massachusetts, United States of America, Bioinformatics Program, College of Engineering, Boston University, Boston, Massachusetts, United States of America, Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

Martin Steffen

Affiliation Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

Avrum Spira

Affiliations The Pulmonary Center, Boston University Medical Center, Boston, Massachusetts, United States of America, Bioinformatics Program, College of Engineering, Boston University, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JB MS AS. Performed the experiments: AB. Analyzed the data: KS JF QRA ML. Contributed reagents/materials/analysis tools: JF SS VS QRA. Wrote the paper: KS JB ML. Coordinated the study: KS. Performed the data analysis: KS. Was responsible for protein isolation, proteomic analyses, and Western blotting: AB. Was responsible for creation of the relational database: JF. Contributed to the development of the relational database: SS VS. Wrote custom software for and participated in proteomic data analysis: QRA. Contributed to the study design: AYK JB. Contributed to the writing of the manuscript: AYK JB ML. Contributed to the data analysis: JF ML. Contributed to conception of the study and design of the proteomics experiments: MS. Conceived the study and oversaw all aspects of the study: AS.