About the Authors

Helen R. Griffin

Affiliation Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom

Darroch H. Hall

Affiliation Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom

Ana Topf

Affiliation Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom

James Eden

Affiliation Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom

A. Graham Stuart

Affiliation Congenital Heart Centre, Bristol Royal Hospital for Children, Bristol, United Kingdom

Jonathan Parsons

Affiliation Paediatric Cardiology Unit, Leeds General Infirmary, Leeds, United Kingdom

Ian Peart

Affiliation Department of Paediatric Cardiology, Alder Hey Royal Children's Hospital, Liverpool, United Kingdom

John E. Deanfield

Affiliation Cardiothoracic Unit, Great Ormond Street Hospital, London, United Kingdom

John O'Sullivan

Affiliation Congenital Heart Unit, Cardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne, United Kingdom

Sonya V. Babu-Narayan

Affiliation Royal Brompton Hospital and National Heart & Lung Institute, Imperial College, London, United Kingdom

Michael A. Gatzoulis

Affiliation Royal Brompton Hospital and National Heart & Lung Institute, Imperial College, London, United Kingdom

Frances A. Bu'Lock

Affiliation Congenital and Paediatric Cardiology Service, Glenfield Hospital, Leicester, United Kingdom

Shoumo Bhattacharya

Affiliation Department of Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Jamie Bentham

Affiliation Department of Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Martin Farrall

Affiliation Department of Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Javier Granados Riveron

Affiliation Institute of Genetics, University of Nottingham, Queen's Medical Centre, Nottingham, United Kingdom

J. David Brook

Affiliation Institute of Genetics, University of Nottingham, Queen's Medical Centre, Nottingham, United Kingdom

John Burn

Affiliation Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom

Heather J. Cordell

Affiliation Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom

Judith A. Goodship

Affiliation Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom

Bernard Keavney

b.d.keavney@ncl.ac.uk

Affiliation Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HRG JD JO SB MF DB JB JAG BK. Performed the experiments: HRG DHH AT JE. Analyzed the data: HRG DHH AT JE MF HC JAG BK. Contributed reagents/materials/analysis tools: AGS JP IP JD JO SVBN MAG FAB SB JB JGR DB. Wrote the paper: HRG AT JAG BK. Contributed to revision of the paper for important intellectual content: DHH JE AGS JP IP JD JO SVB-N MAG FAB SB JB MF JG-R DB JB HC.