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Research Article

cGMP-Dependent Protein Kinase I Is Crucial for Angiogenesis and Postnatal Vasculogenesis

  • Alexandra Aicher equal contributor mail,

    equal contributor Contributed equally to this work with: Alexandra Aicher, Christopher Heeschen

    aicher_a@yahoo.com (AA); dimmeler@em.uni-frankfurt.de (SD)

    Affiliation: Department of Internal Medicine III, J. W. Goethe University, Frankfurt, Germany

    Current address: School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom,

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  • Christopher Heeschen equal contributor,

    equal contributor Contributed equally to this work with: Alexandra Aicher, Christopher Heeschen

    Affiliation: Department of Internal Medicine III, J. W. Goethe University, Frankfurt, Germany

    Current address: Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain

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  • Susanne Feil,

    Affiliation: Interfakultäres Institut für Biochemie, Universität Tübingen, Tübingen, Germany

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  • Franz Hofmann,

    Affiliation: Institut für Pharmakologie und Toxikologie, Technische Universität München, München, Germany

    X
  • Michael E. Mendelsohn,

    Affiliation: Molecular Cardiology Research Institute, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts, United States of America

    X
  • Robert Feil,

    Affiliation: Interfakultäres Institut für Biochemie, Universität Tübingen, Tübingen, Germany

    X
  • Stefanie Dimmeler mail

    aicher_a@yahoo.com (AA); dimmeler@em.uni-frankfurt.de (SD)

    Affiliation: Department of Internal Medicine III, J. W. Goethe University, Frankfurt, Germany

    X
  • Published: March 16, 2009
  • DOI: 10.1371/journal.pone.0004879

About the Authors

Alexandra Aicher, Christopher Heeschen, Stefanie Dimmeler
Department of Internal Medicine III, J. W. Goethe University, Frankfurt, Germany
Susanne Feil, Robert Feil
Interfakultäres Institut für Biochemie, Universität Tübingen, Tübingen, Germany
Franz Hofmann
Institut für Pharmakologie und Toxikologie, Technische Universität München, München, Germany
Michael E. Mendelsohn
Molecular Cardiology Research Institute, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AA CH SF MEM RF SD. Performed the experiments: AA CH SF RF. Analyzed the data: AA CH SF RF SD. Contributed reagents/materials/analysis tools: SF FH MEM RF. Wrote the paper: AA CH RF SD. Made critical revision of the drafted manuscript for important intellectual content: FH MEM.