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Research Article

Investigating Differential Dynamics of the MAPK Signaling Cascade Using a Multi-Parametric Global Sensitivity Analysis

  • Jeongah Yoon,

    Affiliation: Complex Biosystems Modeling Laboratory, Harvard-MIT (HST) Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

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  • Thomas S. Deisboeck mail

    deisboec@helix.mgh.harvard.edu

    Affiliation: Complex Biosystems Modeling Laboratory, Harvard-MIT (HST) Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

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  • Published: February 23, 2009
  • DOI: 10.1371/journal.pone.0004560

About the Authors

Jeongah Yoon, Thomas S. Deisboeck
Complex Biosystems Modeling Laboratory, Harvard-MIT (HST) Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Corresponding Author

Email: deisboec@helix.mgh.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JY TSD. Performed the experiments: JY. Analyzed the data: JY. Wrote the paper: JY TSD.