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Research Article

Mitochondrial Targeted Coenzyme Q, Superoxide, and Fuel Selectivity in Endothelial Cells

  • Brian D. Fink,

    Affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Iowa City Veterans Affairs Medical Center and the University of Iowa, Iowa City, Iowa, United States of America

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  • Yunxia O'Malley,

    Affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Iowa City Veterans Affairs Medical Center and the University of Iowa, Iowa City, Iowa, United States of America

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  • Brian L. Dake,

    Affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Iowa City Veterans Affairs Medical Center and the University of Iowa, Iowa City, Iowa, United States of America

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  • Nicolette C. Ross,

    Affiliation: Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas, United States of America

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  • Thomas E. Prisinzano,

    Affiliation: Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas, United States of America

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  • William I. Sivitz mail

    william-sivitz@uiowa.edu

    Affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Iowa City Veterans Affairs Medical Center and the University of Iowa, Iowa City, Iowa, United States of America

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  • Published: January 22, 2009
  • DOI: 10.1371/journal.pone.0004250

About the Authors

Brian D. Fink, Yunxia O'Malley, Brian L. Dake, William I. Sivitz
Division of Endocrinology and Metabolism, Department of Internal Medicine, Iowa City Veterans Affairs Medical Center and the University of Iowa, Iowa City, Iowa, United States of America
Nicolette C. Ross, Thomas E. Prisinzano
Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas, United States of America

Corresponding Author

Email: william-sivitz@uiowa.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BDF TEP WS. Performed the experiments: BDF YO BLD NCR TEP WS. Analyzed the data: BDF WS. Contributed reagents/materials/analysis tools: TEP WS. Wrote the paper: TEP WS.