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Research Article

Comparing Platforms for C. elegans Mutant Identification Using High-Throughput Whole-Genome Sequencing

  • Yufeng Shen,

    Affiliations: Department of Computer Science, Columbia University, New York, New York, United States of America, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America

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  • Sumeet Sarin,

    Affiliation: Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, New York, United States of America

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  • Ye Liu,

    Affiliation: Department of Computer Science, Columbia University, New York, New York, United States of America

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  • Oliver Hobert mail,

    or38@columbia.edu (OH); ip2169@columbia.edu (IP)

    Affiliation: Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, New York, United States of America

    X
  • Itsik Pe'er mail

    or38@columbia.edu (OH); ip2169@columbia.edu (IP)

    Affiliations: Department of Computer Science, Columbia University, New York, New York, United States of America, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America

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  • Published: December 24, 2008
  • DOI: 10.1371/journal.pone.0004012

About the Authors

Yufeng Shen, Ye Liu, Itsik Pe'er
Department of Computer Science, Columbia University, New York, New York, United States of America
Yufeng Shen, Itsik Pe'er
Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America
Sumeet Sarin, Oliver Hobert
Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, New York, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YS SS YL OH IP. Performed the experiments: YS SS YL IP. Analyzed the data: YS SS YL OH IP. Wrote the paper: YS SS OH IP.