About the Authors

Cedrick D. Dotson

Affiliation Department of Anatomy & Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Lan Zhang

Affiliation Senomyx, Inc., San Diego, California, United States of America

Hong Xu

Affiliation Senomyx, Inc., San Diego, California, United States of America

Yu-Kyong Shin

Affiliation National Institute on Aging/NIH, Baltimore, Maryland, United States of America

Stephan Vigues

Affiliation Department of Anatomy & Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Sandra H. Ott

Affiliation Department of Medicine, Division of Endocrinology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Amanda E. T. Elson

Affiliation Department of Anatomy & Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Hyun Jin Choi

Affiliation Department of Anatomy & Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Hillary Shaw

Affiliation Department of Medicine, Division of Endocrinology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Josephine M. Egan

Affiliation National Institute on Aging/NIH, Baltimore, Maryland, United States of America

Braxton D. Mitchell

Affiliation Department of Medicine, Division of Endocrinology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Xiaodong Li

Affiliation Senomyx, Inc., San Diego, California, United States of America

Nanette I. Steinle

Affiliation Department of Medicine, Division of Endocrinology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Steven D. Munger

smung001@umaryland.edu

Affiliation Department of Anatomy & Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

Authors Lan Zhang, Hong Xu and Xiaodong Li are employees of Senomyx, Inc., where some of these studies were conducted. Authors Cedrick Dotson, Amanda Elson, Nanette Steinle and Steven Munger are inventors on a provisional patent application related to aspects of this work (No. 60/913,795, filed by the University of Maryland, Baltimore).

Author Contributions

Conceived and designed the experiments: CDD XL NIS SDM. Performed the experiments: CDD LZ HX YKS SV SO AEE HJC HS JME BM. Analyzed the data: CDD LZ HX YKS SV SO AEE HJC HS JME BM XL NIS SDM. Wrote the paper: CDD SDM. Edited the paper: SDM CDD SV JEM BM XL NIS.