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Research Article

Premature Aging in Skeletal Muscle Lacking Serum Response Factor

  • Charlotte Lahoute,

    Affiliations: Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France, Inserm, U567, Paris, France

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  • Athanassia Sotiropoulos,

    Affiliations: Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France, Inserm, U567, Paris, France

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  • Marilyne Favier,

    Affiliations: Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France, Inserm, U567, Paris, France

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  • Isabelle Guillet-Deniau,

    Affiliations: Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France, Inserm, U567, Paris, France

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  • Claude Charvet,

    Affiliation: INRA, UR1282 Infectiologie Animale et Santé Publique, Nouzilly, France

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  • Arnaud Ferry,

    Affiliations: UMR S787, Inserm/UPMC-Paris 6/ Institut de Myologie, Paris, France, Université Paris Descartes, Paris, France

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  • Gillian Butler-Browne,

    Affiliation: UMR S787, Inserm/UPMC-Paris 6/ Institut de Myologie, Paris, France

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  • Daniel Metzger,

    Affiliation: IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Department of Functional Genomics, Inserm, U596, CNRS, UMR 7104, Collège de France, Illkirch, Université Louis Pasteur, Strasbourg, France

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  • David Tuil mail,

    david.tuil@inserm.fr (DT); dominique.daegelen@inserm.fr (DD)

    Affiliations: Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France, Inserm, U567, Paris, France

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  • Dominique Daegelen mail

    david.tuil@inserm.fr (DT); dominique.daegelen@inserm.fr (DD)

    Affiliations: Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France, Inserm, U567, Paris, France

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  • Published: December 11, 2008
  • DOI: 10.1371/journal.pone.0003910

About the Authors

Charlotte Lahoute, Athanassia Sotiropoulos, Marilyne Favier, Isabelle Guillet-Deniau, David Tuil, Dominique Daegelen
Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France
Charlotte Lahoute, Athanassia Sotiropoulos, Marilyne Favier, Isabelle Guillet-Deniau, David Tuil, Dominique Daegelen
Inserm, U567, Paris, France
Claude Charvet
INRA, UR1282 Infectiologie Animale et Santé Publique, Nouzilly, France
Arnaud Ferry, Gillian Butler-Browne
UMR S787, Inserm/UPMC-Paris 6/ Institut de Myologie, Paris, France
Arnaud Ferry
Université Paris Descartes, Paris, France
Daniel Metzger
IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Department of Functional Genomics, Inserm, U596, CNRS, UMR 7104, Collège de France, Illkirch, Université Louis Pasteur, Strasbourg, France

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CL AS IGD DT DD. Performed the experiments: CL AS MF AF. Analyzed the data: CL AS IGD AF GBB. Contributed reagents/materials/analysis tools: CC GBB DM DT. Wrote the paper: CL AS DD.