About the Authors

Gino Miele

g.miele@dundee.ac.uk (GM); adriano.aguzzi@usz.ch (AA)

Current address: Translational Medicine Research Collaboration, Sir James Black Centre, University of Dundee, Dundee, United Kingdom

Affiliation Department of Pathology, UniversitätsSpital Zürich, Institute of Neuropathology, Zürich, Switzerland

Harald Seeger

Affiliation Department of Pathology, UniversitätsSpital Zürich, Institute of Neuropathology, Zürich, Switzerland

Denis Marino

Affiliation Department of Pathology, UniversitätsSpital Zürich, Institute of Neuropathology, Zürich, Switzerland

Ralf Eberhard

Affiliation Department of Pathology, UniversitätsSpital Zürich, Institute of Neuropathology, Zürich, Switzerland

Mathias Heikenwalder

Affiliation Department of Pathology, UniversitätsSpital Zürich, Institute of Neuropathology, Zürich, Switzerland

Katharina Stoeck

Affiliation Department of Pathology, UniversitätsSpital Zürich, Institute of Neuropathology, Zürich, Switzerland

Max Basagni

Affiliation Prion Diagnostica Srl, Rho, Italy

Richard Knight

Affiliation The National Creutzfeldt-Jakob Disease Surveillance Unit, Western General Hospital, Edinburgh, United Kingdom

Alison Green

Affiliation The National Creutzfeldt-Jakob Disease Surveillance Unit, Western General Hospital, Edinburgh, United Kingdom

Francesca Chianini

Affiliation Moredun Research Institute, Pentlands Science Park, Edinburgh, United Kingdom

Rudolf P. Wüthrich

Affiliation UniversitätsSpital Zürich, Clinic for Nephrology, Zürich, Switzerland

Christoph Hock

Affiliation Division of Psychiatry Research, University of Zürich, Zürich, Switzerland

Inga Zerr

Affiliation National TSE Reference Center, Department of Neurology, Medical Faculty, Georg-August University, Göttingen, Germany

Adriano Aguzzi

g.miele@dundee.ac.uk (GM); adriano.aguzzi@usz.ch (AA)

Affiliation Department of Pathology, UniversitätsSpital Zürich, Institute of Neuropathology, Zürich, Switzerland

Competing Interests

Max Bassagni has an interest in Prion Diagnostica Srl, which commercializes prion detection assays. All remaining authors declare no conflict of interests.

Author Contributions

Conceived and designed the experiments: GM AA. Performed the experiments: GM DM RE. Analyzed the data: GM HS AA. Contributed reagents/materials/analysis tools: GM HS MH KS MB RK AG FC RW CH IZ AA. Wrote the paper: GM AA.