About the Authors

Rui Wang-Sattler

rui.wang-sattler@helmholtz-muenchen.de

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Yao Yu

Affiliation Bioinformatics Center, Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China

Kirstin Mittelstrass

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Eva Lattka

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Elisabeth Altmaier

Affiliation Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Christian Gieger

Affiliations Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany

Karl H. Ladwig

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Norbert Dahmen

Affiliation Department for Psychiatry, University of Mainz, Mainz, Germany

Klaus M. Weinberger

Affiliation Biocrates Life Sciences AG, Innsbruck, Austria

Pei Hao

Affiliations Bioinformatics Center, Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China, Shanghai Center for Bioinformation Technology, Shanghai, People's Republic of China

Lei Liu

Affiliations Bioinformatics Center, Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China, Shanghai Center for Bioinformation Technology, Shanghai, People's Republic of China

Yixue Li

Affiliations Bioinformatics Center, Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China, Shanghai Center for Bioinformation Technology, Shanghai, People's Republic of China

H.-Erich Wichmann

Affiliations Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany

Jerzy Adamski

Affiliations Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Lehrstuhl für Experimentelle Genetik, Technische Universität München, Munich, Germany

Karsten Suhre

Affiliations Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Faculty of Biology, Ludwig-Maximilians-Universität, Planegg-Martinsried, Germany

Thomas Illig

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Competing Interests

Dr. Weinberger is an employee of Biocrates life sciences AG. This private company offers products and services in the field of targeted quantitative metabolomics research. The other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CG HEW JA KS TI. Performed the experiments: KMW. Analyzed the data: RWS YY KM EL EA CG KHL ND PH LL YL HEW JA KS TI. Contributed reagents/materials/analysis tools: RWS YY JA KS TI. Wrote the paper: RWS YY KM CG JA.