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Research Article

Pattern Recognition in Pulmonary Tuberculosis Defined by High Content Peptide Microarray Chip Analysis Representing 61 Proteins from M. tuberculosis

  • Simani Gaseitsiwe,

    Affiliations: Department of Microbiology, Tumor and Cell Biology Center (MTC), Karolinska Institutet Stockholm, Stockholm, Sweden, The Swedish Institute for Infectious Disease Control (SMI), Stockholm, Sweden

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  • Davide Valentini,

    Affiliation: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

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  • Shahnaz Mahdavifar,

    Affiliation: The Swedish Institute for Infectious Disease Control (SMI), Stockholm, Sweden

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  • Isabelle Magalhaes,

    Affiliations: Department of Microbiology, Tumor and Cell Biology Center (MTC), Karolinska Institutet Stockholm, Stockholm, Sweden, The Swedish Institute for Infectious Disease Control (SMI), Stockholm, Sweden

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  • Daniel F. Hoft,

    Affiliation: Division of Immunobiology, Departments of Internal Medicine & Molecular Microbiology, Saint Louis University Medical Center, Saint Louis, Missouri, United States of America

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  • Johannes Zerweck,

    Affiliation: JPT, Berlin, Germany

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  • Mike Schutkowski,

    Affiliation: JPT, Berlin, Germany

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  • Jan Andersson,

    Affiliation: Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden

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  • Marie Reilly,

    Affiliation: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

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  • Markus J. Maeurer mail

    markus.maeurer@ki.se

    Affiliations: Department of Microbiology, Tumor and Cell Biology Center (MTC), Karolinska Institutet Stockholm, Stockholm, Sweden, The Swedish Institute for Infectious Disease Control (SMI), Stockholm, Sweden

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  • Published: December 09, 2008
  • DOI: 10.1371/journal.pone.0003840

About the Authors

Simani Gaseitsiwe, Isabelle Magalhaes, Markus J. Maeurer
Department of Microbiology, Tumor and Cell Biology Center (MTC), Karolinska Institutet Stockholm, Stockholm, Sweden
Davide Valentini, Marie Reilly
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Simani Gaseitsiwe, Shahnaz Mahdavifar, Isabelle Magalhaes, Markus J. Maeurer
The Swedish Institute for Infectious Disease Control (SMI), Stockholm, Sweden
Daniel F. Hoft
Division of Immunobiology, Departments of Internal Medicine & Molecular Microbiology, Saint Louis University Medical Center, Saint Louis, Missouri, United States of America
Johannes Zerweck, Mike Schutkowski
JPT, Berlin, Germany
Jan Andersson
Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden

Corresponding Author

Email: markus.maeurer@ki.se

Competing Interests

MM is cofounder of Thymed, a company specialized in visualizing cellular immune responses. No financial/competing interest is involved.

Author Contributions

Conceived and designed the experiments: SG MM. Performed the experiments: SG SM IM. Analyzed the data: SG DV SM IM MR MM. Contributed reagents/materials/analysis tools: DV DH JZ MS JA MR. Wrote the paper: SG DV MR MM.