About the Authors

Katsuhiko Nosho

Contributed equally to this work with: Katsuhiko Nosho, Natsumi Irahara, Kaori Shima, Shoko Kure

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

Natsumi Irahara

Contributed equally to this work with: Katsuhiko Nosho, Natsumi Irahara, Kaori Shima, Shoko Kure

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

Kaori Shima

Contributed equally to this work with: Katsuhiko Nosho, Natsumi Irahara, Kaori Shima, Shoko Kure

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

Shoko Kure

Contributed equally to this work with: Katsuhiko Nosho, Natsumi Irahara, Kaori Shima, Shoko Kure

Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America

Gregory J. Kirkner

Affiliation Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Eva S. Schernhammer

Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Ludwig Boltzmann-Institute for Applied Cancer Research, and Applied Cancer Research – Institute for Translational Research, Vienna, Austria, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

Aditi Hazra

Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

David J. Hunter

Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

John Quackenbush

Affiliations Department of Biostatistics, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

Donna Spiegelman

Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

Edward L. Giovannucci

Affiliations Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

Charles S. Fuchs

Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America, Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Shuji Ogino

shuji_ogino@dfci.harvard.edu

Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CF SO. Performed the experiments: KN NI KS SK GJK JQ SO. Analyzed the data: KN NI KS SK GJK ESS AH DJH JQ DS EG CF SO. Contributed reagents/materials/analysis tools: GJK ESS AH JQ DS SO. Wrote the paper: KN NI KS SK DJH JQ EG CF SO.