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Research Article

Genomic Convergence Analysis of Schizophrenia: mRNA Sequencing Reveals Altered Synaptic Vesicular Transport in Post-Mortem Cerebellum

  • Joann Mudge,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Neil A. Miller,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Irina Khrebtukova,

    Affiliation: Illumina Inc., Hayward, California, United States of America

    X
  • Ingrid E. Lindquist,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Gregory D. May,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Jim J. Huntley,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Shujun Luo,

    Affiliation: Illumina Inc., Hayward, California, United States of America

    X
  • Lu Zhang,

    Affiliation: Illumina Inc., Hayward, California, United States of America

    X
  • Jennifer C. van Velkinburgh,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Andrew D. Farmer,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Sharon Lewis,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • William D. Beavis,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Faye D. Schilkey,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Selene M. Virk,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • C. Forrest Black,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • M. Kathy Myers,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Lar C. Mader,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Ray J. Langley,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • John P. Utsey,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Ryan W. Kim,

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Rosalinda C. Roberts,

    Affiliation: Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

    X
  • Sat Kirpal Khalsa,

    Affiliation: Northern New Mexico College, Española, New Mexico, United States of America

    X
  • Meredith Garcia,

    Affiliation: Northern New Mexico College, Española, New Mexico, United States of America

    X
  • Victoria Ambriz-Griffith,

    Affiliation: Northern New Mexico College, Española, New Mexico, United States of America

    X
  • Richard Harlan,

    Affiliation: Northern New Mexico College, Española, New Mexico, United States of America

    X
  • Wendy Czika,

    Affiliation: SAS Institute, Cary, North Carolina, United States of America

    X
  • Stanton Martin,

    Affiliation: SAS Institute, Cary, North Carolina, United States of America

    X
  • Russell D. Wolfinger,

    Affiliation: SAS Institute, Cary, North Carolina, United States of America

    X
  • Nora I. Perrone-Bizzozero,

    Affiliation: Department of Neurosciences, University of New Mexico, Albuquerque, New Mexico, United States of America

    X
  • Gary P. Schroth,

    Affiliation: Illumina Inc., Hayward, California, United States of America

    X
  • Stephen F. Kingsmore mail

    sfk@ncgr.org

    Affiliation: National Center for Genome Resources, Santa Fe, New Mexico, United States of America

    X
  • Published: November 05, 2008
  • DOI: 10.1371/journal.pone.0003625

About the Authors

Joann Mudge, Neil A. Miller, Ingrid E. Lindquist, Gregory D. May, Jim J. Huntley, Jennifer C. van Velkinburgh, Andrew D. Farmer, Sharon Lewis, William D. Beavis, Faye D. Schilkey, Selene M. Virk, C. Forrest Black, M. Kathy Myers, Lar C. Mader, Ray J. Langley, John P. Utsey, Ryan W. Kim, Stephen F. Kingsmore
National Center for Genome Resources, Santa Fe, New Mexico, United States of America
Irina Khrebtukova, Shujun Luo, Lu Zhang, Gary P. Schroth
Illumina Inc., Hayward, California, United States of America
Nora I. Perrone-Bizzozero
Department of Neurosciences, University of New Mexico, Albuquerque, New Mexico, United States of America
Sat Kirpal Khalsa, Meredith Garcia, Victoria Ambriz-Griffith, Richard Harlan
Northern New Mexico College, Española, New Mexico, United States of America
Rosalinda C. Roberts
Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
Wendy Czika, Stanton Martin, Russell D. Wolfinger
SAS Institute, Cary, North Carolina, United States of America

Corresponding Author

Email: sfk@ncgr.org

Competing Interests

Irina Khrebtukova, Shujun Luo, Lu Zhang and Gary P. Schroth are employees of Illumina Inc. Wendy Czika, Stanton Martin and Russell D. Wolfinger are employees of SAS Institute, Cary, NC.

Author Contributions

Conceived and designed the experiments: GPS SFK. Performed the experiments: JM NAM IK IEL GM JJH LS LZ JCvV ADF RJL RWK. Analyzed the data: JM NAM IK IEL GM JJH JCvV ADF SL WB FDS SMV CFB MKM LCM RJL SKK MG VAG REH WC SM RDW NPB GPS SFK. Contributed reagents/materials/analysis tools: NAM GM ADF SL WB FDS SMV CFB MKM LCM JPU RWK RCR WC SM NPB GPS. Wrote the paper: JM SKK MG REH RDW NPB GPS SFK.